Simulate the Physiology & Understand the Pathology

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Computational Life is a young company which has the specialty on computational flow simulations and mathematical models for the medical technology field.

The validated software Digital Avatar Platform (DAP) of Computational Life is modeling human and animal body mathematically. It is testing physiological scenarios for drugs, medical devices and treatment methods.

Circulation system, cerebrospinal fluids, transport of pharmaceutical products throughout the body can be simulated for the human and animal body with DAP. It can also be modified due to the experiment.

They replied to me with a very warm and energetic mood when I wrote them. It is great that there are enthusiastic people in the medical technology field. I am sure that I will hear more about the news of Computational Life in the next days.

Thanks to Christian Contarino, Davide Chieco and Carlo Rivis for their innovative platform which brings a great help for clinicians, researchers, and engineers.

Please check their website for more information.

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Velocity Contours in Iso-Surfaces for The Re-Stenosed Pulmonary Artery

The entrance lenght parts of the inlet and outlet sections are only used for calculation process.

Wall Shear Stress

Pediatric re-stenosed pulmonary artery model is depicted with marked points of unstable wall shear stress (WSS) which brings about the thinner layers by platelets. This means the loss of smooth muscle cells and remodeling risk. Sudden bends and tapering in the geometry induces high velocity gradients and high wall shear stress.

A 3D Patient-Specific Aorta Model which is Segmented by The Visualisation Toolkit

NAFEMS European Conference on Multiphysics Simulation 2018

11th & 12th October 2018
Budapest, Hungary

Technology is changing faster than ever. Global megatrends – such as digitalization, resource scarcity, and the need for renewable energy – drive the demand for innovation and efficient product development. In today’s world of almost limitless computing power, numerical simulations need to be both accessible and accurate in order to enable innovation.

NAFEMS are pleased to announce the fourth European Conference on Multiphysics simulations in October 2018. It will cover the use of Multiphysics simulations in industry.

Source

Virtual Physiological Human Conference 2018 / Zaragoza

Conference Web Link

8th World Congress of Biomechanics / Pekkan Lab

More

Wilhelmina Children’s Hospital / Utrecht Sessions

3 daags kindercardiologie TGA symposium

UMC Utrecht

3D-Printed Artificial Heart Test / #ETH Zurich

Optimizing your workflow in the Mimics Innovation Suite

The Mimics Innovation Suite (MIS) allows you to automate your workflows, potentially saving a lot of time, achieving more consistency, and reducing repetitive work and human error. That is an easy thing to say, but if you do not have much experience with scripting, we all know that it can be tough to get started. If you want to speed up your learning curve and get a head start, then this could be an interesting training for you.

Topics will include:

Basics of Optimizing your Workflow in Mimics 21 and 3-matic 13
How to write your first scripts
Introduction to Python
Hands-on training exercises for creating planning workflows (e.g. loading datasets, performing basic segmentation steps, landmarking, creating anatomical coordinate systems, designing custom implants)

CERTIFICATED ANSYS DISCOVERY LIVE ’3D Modeling, Design & Simulation in real time’

Simscale Certification

Thanks to Anna Flessner and Milad Mafi for the certificate, excellent training documents and lectures. #Simscale

The workshop was including the simulations of

1- Hip Joint Prosthesis and comparison of different materials with displacements

2- Stent Design and Comparison of different materials and different balloon pressures

3- Comparison of different stenosis persentages in carotid artery samples by CFD

Utrecht Medical Center / TGA Symposium

‘Lauded’


Cardiovascular

The 5th ‘The Utrecht Sessions’ for Congenital Heart Disease

The Utrecht Sessions for Congenital Heart Disease was held at the University Medical Center Utrecht on 8-10 February. It was one of the best organized meetings I’ve ever attended.

I had the chance to listen to the work of the most successful pediatric cardiologists and surgeons in the field and to learn a lot about TGA.

I would like to thank Heynric Grotenhuis for the courtesy and help in the pre-seminar correspondence. And I would like to thank Gregor Krings for his support to share my work and to inspirational favour to interdisciplinary research.

I am delighted to have the chance to meet Gregor Krings, Heynric Grotenhuis, Tjark Ebels, Mario Carminati, Tara Bharucha , Petru Liuba, Virpe Puska and Ghadeera Almansoori.

Trando Med

Trando Med will attend MEDICA 2017 in the Dusseldorf Germany from 13-16 November 2017. The booth is Hall 13 Booth F 9-05

Carol Malnati

“- I wanted to be someone that encouraged young women to get involved in math, science, and engineering.”

Today, she’s doing just that.

As a product development engineer in the Medtronic cardiovascular division, Carol has been doing what she loves for more than 25 years. She provided critical technical expertise for the company’s first implantable cardioverter defibrillator and continues to collaborate with engineering teams and physicians to find new ways of doing things.

But on top of her day job, she has taken on another commitment – overseeing the Women in Science and Engineering (WISE) Initiative at the company.

Beginning in the spring of 2017, Medtronic introduced another opportunity that taps into an often overlooked talent pool.  Careers 2.0 is a “returnship” program designed to provide paid internships for female engineers looking to get back into STEM-related careers. Research suggests close to 25 percent of women in engineering careers leave the industry by age 30, citing work culture or family commitments.

“This is a way to bring these talented women back into our technical and managerial ranks,” says Carol. “We are very excited about providing this amazing pool of talent an opportunity at Medtronic.”

“Overall, I want to inspire women,” says Carol. “Whatever your passion is; clean air, fighting hunger, or improving healthcare. Behind the biggest challenges of humanity, there’s an engineer working to find a solution.”

Source

Surgical Planning and 3D Printed Hearts

Alistair Phillips, MD, who is the Co-Chair for the American College of Cardiology, Surgeons Section tells about some of the impacts he has personally experienced using 3D printing in surgical settings as his participation in the 3DHEART program:

“The clinical trial is particularly exciting as it targets specific cases in which understanding of the anatomy will greatly enhance the surgical approach. A 3D printed replica of a patient’s heart will be created as part of the inclusion criteria to be in the study.Using 3D printing gave a better understanding of the Hybrid procedure, and allowed us to perform pulmonary valve replacement with a minimally invasive approach avoiding conventional method that required open-heart surgery. After coming to Cedars-Sinai we refined the pre-ventricular approach by utilizing a 3D printed models of patients’ hearts. We were able to simulate the implant into the right ventricular outflow tract.

Every surgeon is different. The education, experience, aptitudes, and attitude we bring to each equally nuanced and varied patient span an almost limitless spectrum and inform how we may utilize 3D printing for the benefit of our patients. The elegance of 3D printing is that it can create the individualized tools spanning this spectrum.

That said, however, what is not negotiable is the veracity of the models that we are receiving. Various materials and their corresponding colouring or rigidity may serve different functions in the hands of different surgeons, but ultimately we must have the utmost confidence in the fidelity of the models we are utilizing for pre-surgical planning. The more realistic the model is both in anatomical and textural preciousness will greatly enhance the application.

In all honesty, I would advise each hospital to start by really understanding the value proposition 3D printing offers across all specialities and, the culture of their institution. The best way to get answers to these very nebulous, complicated, nuanced directives is by retaining an outside vendor to provide as much of the services as possible, from the proverbial soup to nuts.

The excitement around the 3DHEART clinical trial is so great because it is the first organized, large-scale attempt to collect evidence of the efficacies of 3D printing in the practice of medicine and delivery of healthcare, not only in terms of optimized patient outcomes but also with respect to lower costs. If we can get reimbursement for 3D models, it is without a doubt a game-changer in terms of the practice of medicine, and a life-changer for many of our patients.”

Source

Flow Testing Dynamic Systems with 3D Printed Patient-Specific Heart Models

Without the 3D printed models, we wouldn’t have been able to come up with a way to do the procedure in advance.

—C. HUIE LIN, M.D
Adult congenital and interventional cardiologist.

3D Print Bureau of Texas has partnered with physicians at Houston Methodist Hospital to create cardiac models for applications such as assessing the size and attachment site of a right atrial malignancy. Accurate physical replications of patient anatomy can even undergo testing in a dynamic system such as replicating the severity of aortic stenosis using flow testing.

3D Print Bureau of Texas also worked with Houston Methodist DeBakey Heart and Vascular Center on a complex case involving a young patient born with a wide-open leaking pulmonary valve. The patient could not take blood transfusions and have been turned down by two medical centres concerned she would not make it through surgery.

With a 3D printed model of the patient’s heart, Lin devised a plan that required very little blood loss, which resulted in a successful operation for the little patient.

Source

The Impacts of Cardiac MRI on Congenital Surgical Results

On October 19 Koc University presented “The Impacts of Cardiac MRI on Congenital Heart Surgical Results,” a public symposium at Koc University Hospital Artlab Conference Hall that explored the benefits of cardiac MRI scans for depicting the congenital heart anatomy.

The symposium began with a presentation by Prof. Afksendiyos Kalangos. He was followed by renowned pediatric cardiovascular surgeons and cardiologists Prof. Atıf Akçevin, Prof. Alpay Çeliker, Prof. Aphrodite Tzifa, A. Professor Tijen Alkan- Bozkaya and the radiologists Dr. Serhat Aygün, A. Professor Özdil Başkan who presented their own experiences, demonstrating a vast range of approaches to defining the context.

Prof. Kerem Pekkan presented his studies with MRI imaging and cardiovascular mechanics in the cases of blood flow dynamics, biomaterial tests, patient-specific vascular materials and surgical planning for congenital heart diseases. His signified projects were one of the fascinating parts of the symposium for participants.