Category: Biophysics

Trando Med

Trando Med will attend MEDICA 2017 in the Dusseldorf Germany from 13-16 November 2017. The booth is Hall 13 Booth F 9-05

Carol Malnati

“- I wanted to be someone that encouraged young women to get involved in math, science, and engineering.”

Today, she’s doing just that.

As a product development engineer in the Medtronic cardiovascular division, Carol has been doing what she loves for more than 25 years. She provided critical technical expertise for the company’s first implantable cardioverter defibrillator and continues to collaborate with engineering teams and physicians to find new ways of doing things.

But on top of her day job, she has taken on another commitment – overseeing the Women in Science and Engineering (WISE) Initiative at the company.

Beginning in the spring of 2017, Medtronic introduced another opportunity that taps into an often overlooked talent pool.  Careers 2.0 is a “returnship” program designed to provide paid internships for female engineers looking to get back into STEM-related careers. Research suggests close to 25 percent of women in engineering careers leave the industry by age 30, citing work culture or family commitments.

“This is a way to bring these talented women back into our technical and managerial ranks,” says Carol. “We are very excited about providing this amazing pool of talent an opportunity at Medtronic.”

“Overall, I want to inspire women,” says Carol. “Whatever your passion is; clean air, fighting hunger, or improving healthcare. Behind the biggest challenges of humanity, there’s an engineer working to find a solution.”

Source

ISCOMS 2017 at University of Groningen

Many thanks to University Medical Center Groningen for the oral sessions and workshops of 3D Lab, LVAD treatment, Dissection of Brain, CABG treatment, IV Injections and Nuclear Medicine.

Starfish Medical – VivitroLabs – ProtomedLabs


Ece Tutsak – Banu Köse – Vincent Garitey

20. National Liquid State Physics Symposium 16 December 2016

20. National Symposium on  Liquid State Physics was held in Piri Reis University.

The symposium was obtaining various studies about liquids as water and climate change, simulating strait systems, oceans, spin glass phases, liquid crystals, serum transferring,  swollen gells, GO composites, metals with  glass-like structure, super hidrophobic polistren and, biofluids {yes, this was mine ;) }.

It was an incontrovertible experience for me that i could meet new studies in the field and spend nameable times with  physics authors.

Many thanks to organizing comitee (especially to Gülşen Evingür) and Sevtap Yıldız Özbek.

The website of the symposium is here.

ICPT – GEFIK 2016

I had chance to present my works to authors and answer the questions of young curious physicisits at GEFIK2016 in Ege University. Discussing about medical physics and classical mechanics with physicists was a peerless experience.

3D Printed Aorta

A pediatric aorta model reconstructed from the 3D CT images.

‘Go with the flow’ by Victoria Stoll

The British Heart Foundation (BHF) announced the winners of its annual ?Reflections of Research? image competition, reflecting the charity?s research into heart and circulatory disease.
The winning image ? titled ?Go with the flow,? by Victoria Stoll, a BHF-funded researcher at the University of Oxford ? captures the blood flowing within an adult heart frozen in time. Blood flows within the main pumping chambers (ventricles) of the heart and the vessels leaving the heart. The blue flow is blood that lacks oxygen and is travelling to the lungs. The red flow is blood that has been through the lungs and received oxygen and is now ready to be pumped around the body.
Stoll is using this type of imaging, four-dimensional cardiac magnetic resonance imaging (MRI), to look at the blood flow in four dimensions within the hearts of people with heart failure, whose hearts are not pumping effectively. She has already found that in people with severe heart failure the blood flows around the heart in a more disordered and disrupted pattern.

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Me in The Old Lab and The Oxygenator

PRINT THYSELF

This sort of procedure is becoming more and more common among doctors and medical researchers. Almost every day, I receive an e-mail from my hospital?s press office describing how yet another colleague is using a 3-D printer to create an intricately realistic surgical model?of a particular patient?s mitral valve, or finger, or optic nerve?to practice on before the actual operation. Surgeons are implanting 3-D-printed stents, prosthetics, and replacement segments of human skull. The exponents of 3-D printing contend that the technology is making manufacturing more democratic; the things we are choosing to print are becoming ever more personal and intimate. This appears to be even more true in medicine: increasingly, what we are printing is ourselves.

Source: Newyorker

Measure Your Blood Flow

The inventors of the new ?epidermal electronic? sensor system say it is ready for use in a clinical setting, specifically for monitoring skin health, for example in patients who have recently had skin grafts. They say down the road it may also be possible to use it inside the body. In a recent demonstration, the researchers showed that the device can record accurate data from human subjects about the flow of blood in larger vessels, specifically veins in the forearm, as well as in the network of tiny vessels near the surface of the skin.

Compared with state-of-the-art methods for noninvasively measuring blood flow, which rely on optical systems or ultrasound technology, the new sensor is much simpler and less expensive, says John Rogers, one of the inventors and a professor of materials science and engineering at the University of Illinois at Urbana-Champaign. More importantly, he says, it is much less sensitive to motion thanks to the way it ?intimately laminates? to the skin.

Characteristics of the blood flow in any given tissue are a good indicator of that tissue?s health. Some conditions, like infection and inflammation, can lead to an increase in local blood flow, whereas others, like atherosclerosis, heart failure, and diabetes, can cause a decrease. If doctors could precisely and even continuously monitor this flow, they could better tailor care to individual patients and conditions.

Source

3D Printing for Pediatric Cardiothoracic Surgeons

Having worked in product development for the past few years, Dr. Enrique Garcia had seen what 3D printers were capable of and began investigating the possibilities for creating models for pediatric cardiologists to use before an operation. She began by asking surgeons from around the country what they thought of the idea. To say that their response was overwhelmingly positive is an understatement. The value of this idea was immediately apparent.

?Pediatric heart surgery is the hardest thing that I can imagine a person doing. A surgeon doesn?t know what he?s going to see until he opens a child?s chest. Every heart is different and every cardiopathy is different,? said Garcia. ?A baby?s heart is the size of a walnut, and surgeons need to go in and move around structures that are as small and thin as a human hair; and they?re doing it with their own two hands. And all of this is occurring against a ticking clock.?
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?Having something in your hands, and being able to turn it any way you want, and to be able to cut and open it up and see the inside; and to be able to physically hold it, to feel it, is something that can?t be replicated in a computer.?

Read More in the source.

cSound

Researchers have created software that can model internal organs in ‘extreme 4D’.
The system, dubbed cSound, is currently being used by cardiologist Bijoy Khandheria, who has been fixing broken hearts for more than three decades.

Dr Khandheria describes the images as ‘exquisite’, and says it’s like opening up someone’s chest and watching their heart beat.’

‘Traditionally, ultrasound has allowed us to see the heart but not in as much detail as we might like,’ he said.
‘We used the signal to image the heart layer by layer, almost like a butcher using a knife, and then mentally splice the layers together to see the whole picture’.
Dr Khandheria and his colleagues at Aurora St Luke’s Medical Center in Milwaukee, have recently started ‘extreme 4D’ software.
The images are so clear that it allows doctors to see how blood swirls around clots in arteries.
This can then be used to measure the severity of blood leakage around the valves and assess the damages.
‘It’s almost as if I took out the valve and started turning it with my hands,’ said Dr Khandheria.

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The special session for the women in the field of cardiovascular surgery – The 64th Istanbul ESCVS

International Congress of the European Society for Cardiovascular and Endovascular Surgery (ESCVS) will be held on March 26th – 29th, 2015 in İstanbul in collaboration with International Congress of Update Cardiology and Cardiovascular Surgery.

The congress scientific program includes a session for women in cardiovascular surgery which will be held on March 28th.

Abstract Submission Deadline
December 22, 2014
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Notification of Abstract Acceptance
January 2, 2015
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Early Registration
until November 7, 2014

ESCVS 2015 Web Site

The Horizon for Mechanical Circulatory Support

Filmed at the 2014 STS Annual Meeting in Orlando, Florida, this roundtable discussion focuses on mechanical circulatory support. John Kern moderates the discussion with Pavan Atluri and Francis Pagani. The panelists discuss mechanical circulatory support, LVAD therapy, and heart transplantation. The discussion concludes with thoughts on the future of mechanical circulatory support.

Source:  CTS

3D Bio-Printing Project of Sabancı University

For the first time in the world, tissue structures were created by using self-supported live cells in a 3D bio-printer from medical images in the 3D Tissue and Organ Printing Project.

Sabancı University Faculty of Engineering and Natural Sciences? Manufacturing Systems Program professor Bahattin Koç and his stedents; Can Küçükgül, Saime Burçe Özler, Forough Hafezi printed artificial tissue construct at the Nanotechnology Research and Application Center (SUNUM) using self-supported live cells in a  3D bio-printing system.

The 3D Tissue and Organ Printing Project team used live human dermal fibroblast cells as bio-ink to print a part of aortic tissue.  Human blood vessel tissue consists of mainly three types of cells: fibroblast, endothelial  and smooth muscle.  Fibroblast cells are the main cells of connective tissues.  They synthesize the extracellular matrix and collagen protein needed for tissues.  Endothelium is the thin inner layer of cells of blood vessels.  Smooth muscle cells are found in inner organs such as blood vessels, esophagus and intestines.  The scientists continue their efforts to maturate the blood vessel tissue created by fibroblasts as well as endothelial and smooth muscle cells in a bioreactor.

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17th U.S. National Congress on Theoretical & Applied Mechanics

Every four years since 1950 the leading mechanics researchers  have convened the U.S. National Congress on Theoretical and Applied Mechanics. All mechanics researchers and students are invited for the 17th  Congress on the beautiful Big Ten campus at Michigan State University. The sessions will be held at the Kellogg Hotel and Conference Center on Michigan State University’s campus.

Many thanks to Seungik Baek for his kind invite us Cardiovascuar Mechanics Minisymposia:

The goal of this minisymposium is to provide the state of the art in theoretical and computational methods applied to the cardiovascular mechanics including computational and constitutive modeling, theoretical vascular mechanics analysis, and cardiovascular design technologies. Topics may include, but are not limited to cardiovascular fluid and/or solid mechanics, cardiovascular diseases and treatment, optimization techniques. We believe that you would be an excellent contributor to this session based on your many exceptional works in the fields of theoretical and computational mechanics to cardiovascular problems.

The 14th Annual International Symposium on Congenital Heart Disease

The 14th Annual International Symposium on Congenital Heart Disease will feature a world-class faculty of domestic and international experts in Cardiology, Cardiac Critical Care, Cardiac Surgery, Nursing, Hospital Administration, and Ethics. This year the conference will focus on Diseases of the Cardiac Valves from the Fetus to the Adult. The program will include didactic, case-based, and interactive presentations as well as pathologic heart specimens and practical workshops. Special tracks dedicated to cardiovascular nursing and hospital administration will be included making this a truly team-based symposium.

Click for the Symposium Web Page.

Click for Symposium Document.

The World Congress of Biomechanics (WCB) 2014

Registration and abstract submission are now open for The World Congress of Biomechanics (WCB) 2014. The World Congress is the most comprehensive global meeting on all topics related to biomechanics and is held once every four years. The next meeting will be in Boston, Massachusettson July 6-11, 2014.

Submission Timeline

  • November 15, 2013 ? January 15, 2014. Due to limited podium presentation slots, early submission recommended.
  • Student Paper Competition sponsored by ASME Bioengineering Division; requires abstract submission by currently enrolled students at the BS, MS, and PhD levels

Submissions for podium and poster presentations include any area of biomechanics and related areas, including bioheat transfer, biomaterials, ergonomics, medical devices, new testing devices and technologies, and tissue engineering. In particular, biomechanical studies ranging from the molecular level (e.g., DNA mechanics and mechanotransduction) to whole organisms (e.g., from animal flight to human sports biomechanics) are welcome.

Abstracts should be submitted on-line at http://wcb2014.com/event-info/call-for-papers/ and will be reviewed on a continuous basis. Early submission is encouraged! Note that WCB2014 follows a US holiday weekend (July 4, Independence Day) that may affect your travel plans.

Functional blood vessels regenerated in vivo from human induced pluripotent stem cells

Vasculogenesis ? the process of blood vessel formation through a de novo production of endothelial cells (ECs, or those forming a thin layer lining the interior surface of blood and lymphatic vessels) ? is a vital tool in regenerative medicine, tissue engineering, and, in particular, the battle against vascular disease, the leading cause of mortality in the United States. (More than one in three Americans (36.9%) suffer from heart disease, and by 2030, an estimated 116 million people in the United States (40.5%) will have some form of cardiovascular disease.) More specifically, generating functional, long-lasting vasculogenic cells is a key but elusive component in human induced pluripotent stem (hiPS) research. Recently, however, researchers at Harvard University and Massachusetts General Hospital successfully generated endothelial cells from healthy donors’ hiPS cells to form stable functional blood vessels in vivo. Moreover, they developed an approach to generate mesenchymal precursor cells (MPCs, or multipotent stromal, or connective tissue, cells that can differentiate into a variety of cell types including perivascular cells ? another component of vessel wall) from hiPS cells in parallel, and also generated functional blood vessels in vivo using these endothelial and multipotent stromal derived cells from the same hiPS cell line. Beyond this, and in terms of clinical translation, the team successfully generated ECs and MPCs from Type 1 Diabetic patient-derived hiPS cell lines and also used them to generate blood vessels in vivo.

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