Category: BioFluidLab

Women in 3D Printing

I was the guest of Women in 3D Printing this week.

The full-page is on this page: https://womenin3dprinting.com/banu-kose/

Thanks to Nora Toure for all the great work she has done and for bringing us together.

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Institute of Physics / Challenges in Cardiocascular Flow

A joint meeting showcasing current work addressing the complex challenges in cardiac flow modeling, particularly focusing on the work of early career researchers (source).

Physics

Liquid State Physics in Turkey

22. Liquid State Symposium (22. Sıvı Hal Senpozyumu) took place on 7th December 2018 in Piri Reis University.
It was very proud to be together with the physicist academics I knew and admired since my undergraduate years.
I find myself lucky to see the Prof. Zehra Akdeniz that I have always admired and exemplified. I could finally meet Prof. Nihat Berker who is not only a famous physicist but also an intellectual on comparative literature readings.

Thanks to Dr. Ozan Sarıyer and Dr. Gulsen Evingur for organizing this meeting.

The symposium program link

Prof Pekkan presented biological flow researches of his lab, and I presented a sample case of a pediatric aortic blood flow comparison study which is done with the great help of Dr. Ece Salihoglu.

Simulate the Physiology & Understand the Pathology

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Computational Life is a young company which has the specialty on computational flow simulations and mathematical models for the medical technology field.

The validated software Digital Avatar Platform (DAP) of Computational Life is modeling human and animal body mathematically. It is testing physiological scenarios for drugs, medical devices and treatment methods.

Circulation system, cerebrospinal fluids, transport of pharmaceutical products throughout the body can be simulated for the human and animal body with DAP. It can also be modified due to the experiment.

They replied to me with a very warm and energetic mood when I wrote them. It is great that there are enthusiastic people in the medical technology field. I am sure that I will hear more about the news of Computational Life in the next days.

Thanks to Christian Contarino, Davide Chieco and Carlo Rivis for their innovative platform which brings a great help for clinicians, researchers, and engineers.

Please check their website for more information.

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Virtual Physiological Human Conference 2018 / Zaragoza

Conference Web Link

8th World Congress of Biomechanics / Pekkan Lab

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3D-Printed Artificial Heart Test / #ETH Zurich

Trando Med

Trando Med will attend MEDICA 2017 in the Dusseldorf Germany from 13-16 November 2017. The booth is Hall 13 Booth F 9-05

Surgical Planning and 3D Printed Hearts

Alistair Phillips, MD, who is the Co-Chair for the American College of Cardiology, Surgeons Section tells about some of the impacts he has personally experienced using 3D printing in surgical settings as his participation in the 3DHEART program:

“The clinical trial is particularly exciting as it targets specific cases in which understanding of the anatomy will greatly enhance the surgical approach. A 3D printed replica of a patient’s heart will be created as part of the inclusion criteria to be in the study.Using 3D printing gave a better understanding of the Hybrid procedure, and allowed us to perform pulmonary valve replacement with a minimally invasive approach avoiding conventional method that required open-heart surgery. After coming to Cedars-Sinai we refined the pre-ventricular approach by utilizing a 3D printed models of patients’ hearts. We were able to simulate the implant into the right ventricular outflow tract.

Every surgeon is different. The education, experience, aptitudes, and attitude we bring to each equally nuanced and varied patient span an almost limitless spectrum and inform how we may utilize 3D printing for the benefit of our patients. The elegance of 3D printing is that it can create the individualized tools spanning this spectrum.

That said, however, what is not negotiable is the veracity of the models that we are receiving. Various materials and their corresponding colouring or rigidity may serve different functions in the hands of different surgeons, but ultimately we must have the utmost confidence in the fidelity of the models we are utilizing for pre-surgical planning. The more realistic the model is both in anatomical and textural preciousness will greatly enhance the application.

In all honesty, I would advise each hospital to start by really understanding the value proposition 3D printing offers across all specialities and, the culture of their institution. The best way to get answers to these very nebulous, complicated, nuanced directives is by retaining an outside vendor to provide as much of the services as possible, from the proverbial soup to nuts.

The excitement around the 3DHEART clinical trial is so great because it is the first organized, large-scale attempt to collect evidence of the efficacies of 3D printing in the practice of medicine and delivery of healthcare, not only in terms of optimized patient outcomes but also with respect to lower costs. If we can get reimbursement for 3D models, it is without a doubt a game-changer in terms of the practice of medicine, and a life-changer for many of our patients.”

Source

Flow Testing Dynamic Systems with 3D Printed Patient-Specific Heart Models

Without the 3D printed models, we wouldn’t have been able to come up with a way to do the procedure in advance.

—C. HUIE LIN, M.D
Adult congenital and interventional cardiologist.

3D Print Bureau of Texas has partnered with physicians at Houston Methodist Hospital to create cardiac models for applications such as assessing the size and attachment site of a right atrial malignancy. Accurate physical replications of patient anatomy can even undergo testing in a dynamic system such as replicating the severity of aortic stenosis using flow testing.

3D Print Bureau of Texas also worked with Houston Methodist DeBakey Heart and Vascular Center on a complex case involving a young patient born with a wide-open leaking pulmonary valve. The patient could not take blood transfusions and have been turned down by two medical centres concerned she would not make it through surgery.

With a 3D printed model of the patient’s heart, Lin devised a plan that required very little blood loss, which resulted in a successful operation for the little patient.

Source

The Impacts of Cardiac MRI on Congenital Surgical Results

On October 19 Koc University presented “The Impacts of Cardiac MRI on Congenital Heart Surgical Results,” a public symposium at Koc University Hospital Artlab Conference Hall that explored the benefits of cardiac MRI scans for depicting the congenital heart anatomy.

The symposium began with a presentation by Prof. Afksendiyos Kalangos. He was followed by renowned pediatric cardiovascular surgeons and cardiologists Prof. Atıf Akçevin, Prof. Alpay Çeliker, Prof. Aphrodite Tzifa, A. Professor Tijen Alkan- Bozkaya and the radiologists Dr. Serhat Aygün, A. Professor Özdil Başkan who presented their own experiences, demonstrating a vast range of approaches to defining the context.

Prof. Kerem Pekkan presented his studies with MRI imaging and cardiovascular mechanics in the cases of blood flow dynamics, biomaterial tests, patient-specific vascular materials and surgical planning for congenital heart diseases. His signified projects were one of the fascinating parts of the symposium for participants.

Heart Flow

Using data from a standard CT scan, the non-invasive HeartFlow Analysis creates a personalized 3D model of the coronary arteries and analyzes the impact that blockages have on blood flow. See the website: http://www.heartflow.com/

Aorta Aneurysm

IFG26 – Statistical Physics Days

26th Statistical Physics Days were held in İzmir Institute of Technology.

During the program organization, Prof. Nejat Bulut’s dedication and careful attention to every detail was so amazing that it will be a very nice experience in my mind.

It was an honor to be among the successful physicist academicians and to listen to their work. It was also my chance that I had the opportunity to talk about my own practice and find the opportunity to discuss it with very precious professors.

K. Banu Kose

Starfish Medical – VivitroLabs – ProtomedLabs


Ece Tutsak (Left) – Banu Köse(Middle) – Vincent Garitey(Right)

VOKSEL 3D Event in Istanbul

Voksel’s Anatomical Modeling, Surgical Planning, 3D Printing with Engineer – Surgeon Collaboration Training‘ was held on 23rd February in Istanbul.

I had the chance to share my experiences in image processing and modeling with the participants. I would like to thank Kerem Girgin, Erbil Oğuz, Samet Serbest and Cansu Çeltik from Voksel. It was great to be a part of Voksel team, and meeting with the participants who were aware of the benefits of interdisciplinary collaborations and patient-specific planning very well.

Surgical Planning and 3D Printing Meeting

Vivitro Pulse Duplicator Training in Protomed Labs

http://www.protomedlabs.com

It was really a great experience at  Protomed Labs in Aix-Marseille University. I really enjoyed learning about hydrodynamic testing requirements, Vivitro Pulse Duplicator, its calibration, flow testing, heart valve testing, and at the same time  practicing.

Thanks to Prof. Kerem Pekkan for suggesting this training for Ece Tutsak and me.

I would like to express my sincere thanks and gratitude to  Karim Mouneimne and Vincent Garitey for all the kind care they took, regarding the training, sharing their expertise to us, the  detail notes, all the answers whenever required etc. in Protomed Labs.

I hopefully will be able to implement it further into my field.  This got me inspired and ready to go!

For More

Laser Doppler Velocimetry

Laser Doppler velocimetry is used in hemodynamics research as a technique to partially quantify blood flow in human tissues such as skin. Within the clinical environment, the technology is often referred to as laser Doppler flowmetry (LDF). The beam from a low-power laser (usually a laser diode) penetrates the skin sufficiently to be scattered with a Doppler shift by the red blood cells and return to be concentrated on a detector. These measurements are useful to monitor the effect of exercise, drug treatments, environmental, or physical manipulations on targeted micro-sized vascular areas.

The laser Doppler vibrometer is being used in clinical otology for the measurement of tympanic membrane (eardrum), malleus (hammer), and prosthesis head displacement in response to sound inputs of 80- to 100-dB sound-pressure level. It also has potential use in the operating room to perform measurements of prosthesis and stapes (stirrup) displacement.

My Lab Drawings – II

A pulmonary artery. Actually this was the first step of my master thesis.

My Lab Drawings – I

Beliz and me in the lab.

His name is tramp carotid :)